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Moving from Behavioral Observation to Neural Architecture: A Call for Empirical Examination

For too long, mental health and personality theory have relied on symptom-based observations.
Neural Architecture - 144 Phenotype Framework

I am releasing the latest evolution of the 144 Phenotype Framework - a first-principles Neural Operating System designed to map cognitive diversity at the architectural level.

What This Work Proposes

Rather than clustering symptoms, this framework models the antagonistic organization of large-scale neural systems (DMN, TPJ, DLPFC, valuation networks, executive control systems) into a coherent, finite architecture of 144 neurocognitive configurations.

The Master Map (v1.1)

The Master Map (v1.1) is now publicly available.

The scientific community is invited to examine, stress-test, refine, or challenge this architecture through:

The framework is falsifiable by design.

It stands as a structural hypothesis of human neurodiversity - open to examination, independent replication, and theoretical expansion.

Access the latest version (v1.1) on GitHub:

144 Phenotype Framework - Master Map v1.1 →
#Neuroscience #CognitiveScience #Psychiatry #Neurodiversity #RDoC #NetworkNeuroscience #OpenScience
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